A new engineered molecule shows promise as an antidote for carbon monoxide (CO) poisoning with fewer side effects than other remedies currently being tested.
This is according to research from the University of Maryland School of Medicine in the United States.
“Carbon monoxide is the most common poison in America and in the world, and there’s no antidote for it,” said Dr Mark Gladwin, dean of the School of Medicine and principal investigator of the lab that produced the study.
“When people die in house fires, it’s usually due to carbon monoxide poisoning.”
It can also come from operating any kind of combustion in an enclosed space, including a grill, a diesel generator or an automobile.
The researchers published the findings about their engineered molecule, RcoM-HBD-CCC, in the Proceedings of the National Academy of Sciences in August (2025).
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